Creating a new AD domain and moving the machines

Hi all.

We have a SEP Manger 12.1 running on windows 2008 R2  and several laptops/servers (clients) connected to the sepm. All of them in our windows domain A (and of course the SEPM). 

We are creating a new AD domain, let say windows domain B. 

So I was wondering whether  we  have to modify something in our SEPM so the machines clients are able to continue receving updates from the SEPM?

the SEPM has to be migrated to the new windows domain B as well.  is it necessary to remove the sep clients and even the manager and then reinstall everything within the new microsoft AD domain B?

Thanks