Disable port 80 on SEPM group

We have a software that the vendor says does not work well with Symantec 12.1. (works with SEP 11) Said it has to do with the communication between SEPM and Client and port 80. Can we setup a group in the SEPM that would disable using port 80 and allow the others like 443

Upgrading from 11 - 12.1.5