SEP in VDI - Quarantine Best Practices

I'm looking at the best practices regarding SEP and a non-persistent VDI infrastructure. I'm confused how the quarantine will work for those clients. I figured I would have to deploy a central quarantine server, but the article below states that a central quarantine server is not recommended if you have less than 10,000 endpoints.

http://www.symantec.com/business/support/index?page=content&id=TECH104755

So I have two questions. 1) What's the best way to configure the quaratine for VDI clients? 2) Why won't a central quarantine server work well for under 10,000 clients? I believe having the quarantine on a central server will be a great benefit, instead of going to the individual workstations and grabbing the file to analyze.

Thank you!